Biochemistry 300                       Bioinformatics

Subject                                                                                    Week       Chapter(s)      Lab  

Genome Sequence Acquisition                                                       1                     2           DQ 1-39             

Unicellular Genomes                                                                     2                     2           DQ 40-74  

Metazoan Genomes / Human Genome                                             3                     2          DQ 75-97       

Comparative Genomics/Evolution of Genomes                                4                     3          DQ 1-43                            

Genome Identifications / Biomedical Research                                5                     3          DQ 44-81      

Exam 1 / Field Trip 1                                                                    6                     --          --                        

Genomic Variations / Genomics of Aging/ Ethics of Genomics           7                     4          DQ 1-39

Introduction to Microarrays / Alternate Uses of Microarrays               8                     6          DQ 1-44           

Applied Research with Microarrays / Improving Health Care             9                     7           DQ 1-37     

Proteonomics: 3D Structures, Interaction, & Measuring Proteins       10                     8          DQ 1-32

Genomic Circuits in Single Genes                                                  11                   10          DQ 1-33                                 

Exam 2 / Field Trip 2                                                                   12                    --          --                    

Integrated Genomic Circuits                                                         13                   11          DQ 1-33 

Synthetic Biology                                                                        14                    11          DQ 34-59

Modeling Whole Genome Circuits                                                 15                    12          DQ 1-12                                                        

Final Exam                                                                                 16                    --           --                 

Guest Lecture: Organelle Genetics and Genomics       

Grading-           Lecture             50% (2 Exams @ 12.5% each, 1 Final @ 25%)

                        Lab                  50% (Weekly Lab Assignments)

The text for the course will be: “Discovering Genomics, Proteomics, & Bioinformatics” by Campbell & Heyer, 2^nd Edition.  This book is available at the bookstore.  The laboratory questions come from the textbook as well.  Material needed for lab can be accessed at: www.GeneticsPlace.com.  

Contact:           Prof. James Godde

                        HT 404

                        Phone: 2350

 Course Objectives

Upon completion of the course, students should be able to:

1) Understand methods and research questions in bioinformatics

2) Analyze real data

3) Engage in a realistic learning environment

4) Utilize online databases

5) Appreciate the complexity of research systems

6) Integrate different types of information

7) Reconsider cells as intracellular ecosystems

8) Integrate bioinformatics with biology