Biochemistry 300 Bioinformatics
Subject
Week
Chapter(s)
Lab
Genome Sequence Acquisition
1
2
DQ 1-32
Comparative Genomics /
Evolution of Genomes
2
2,
3
DQ 35-44, 1-16
Genome Identifications /
Biomedical Research
3
3
DQ 17-40
Diversity/
Genomic Variations /
Cell Death
4
4
DQ 1-33
Ethics of Genomics/ Exam 1
5
4
DQ 34-63
Field Trip 1
6
--
--
Introduction to Microarrays
7
6
DQ 1-34
Alternate Uses of Microarrays / Cancer and Microarrays
8
6,
7 *
Improving Health Care with Microarrays
9
7 **
Intro to Proteomics / 3D Structures & Interactions
10
8
DQ 1-49
Measuring Proteins
11
8
DQ 50-71
Field Trip 2
12
--
--
Exam 2
13
-- --
Genomic Circuits in Single Genes
13 & 14
10
DQ 1-31
Simple & Complex Integrated Genomic Circuits
15
11 DQ 1-37
Synthetic Biology / Modeling Circuits
16
11,
12
DQ 38-52, 1-12
Final Exam
--
* DQ 36-39, 45-55,
60-67, 72-74, 1-10
** DQ 20-23, 34-35, 39-44, 57-63, 73-77, 83-90
Grading- Lecture 50% (2 Exams @ 12.5% each, 1 Final @ 25%)
Lab 50% (Weekly Lab Assignments)
The text for the course will be: “Discovering Genomics, Proteomics, & Bioinformatics” by Campbell & Heyer, 2nd Edition. This book is available at the bookstore. The laboratory questions come from the textbook as well. Material needed for lab can be accessed at: www.GeneticsPlace.com.
Contact: Prof. James Godde
HT 404
Phone: 2350
Course Objectives
Upon completion of the course, students should be able to:
1) Understand methods and research questions in bioinformatics
2) Analyze real data
3) Engage in a realistic learning environment
4) Utilize online databases
5) Appreciate the complexity of research systems
6) Integrate different types of information
7) Reconsider cells as intracellular ecosystems
8) Integrate bioinformatics with biology