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Dr. James Godde

James GoddeProfessor of Biology

Contact Information

Phone: 309-457-2350
Email:
jgodde@monm.edu

Office: Rm. 244, CSB

Office Hours

MWF: 10 am; MF: 1 pm

Education

B.S. 1987, Western Illinois University
Ph.D. 1993, University of Illinois
Post-doc, National Institutes of Health

Courses taught

Cell Biology, Genetics, Molecular Biology, Microbiology, Life on Earth, Biotechnology and Human Values, Bioinformatics, Global Perspectives: World Impact of East Asian Science, Introduction to the Liberal Arts, The Tao of Travel, Sacred Places, Wilderness: Rainforest Ecosystems, Wilderness: Galapagos Ecosystems, Wilderness: Caribbean Ecosystems, Introduction to Environmental Science, Environmental Microbiology: the Extremophiles, Plants and Society, 3D Animation, Advanced 3D Animation (College for Kids)

Research Interests

I am interested in biodiversity and have been studying the biodiversity of both Southeast Asia as well as the Lake Superior region of the U.S. and Canada.  My molecular approach to biodiversity research is to collect blood sucking organisms such as leeches or mosquitoes and to perform PCR on the digestive tract extracts of these creatures in order to determine their most recent blood meal.  This fall, my SOfIA group hopes to travel to Isle Royale National Park and return to Monmouth with mosquitoes who have feasted on moose, wolf, or bear, among other mammals.  I need students who would perform PCR on these samples and sequence it in order to study the biodiversity of our collection area.

 Other projects in my laboratory involve computer-based analysis of genomic sequences, or bioinformatics.  People who study this field of science are usually called “data miners” since they take large amounts of data and extract important sequences from them.  Since I’m more concerned with repetitive, or junk, DNA, my students are more akin to “data junk collectors”, or if you prefer, “bioinfomaniacs”.  Focus here centers on the identification and analysis of sequences which have been transferred among bacteria or between eukaryotes and bacteria via horizontal gene transfer, or HGT, as opposed to vertically (from parents to offspring) like the majority of gene transfer.

Recent Publications

Godde, J.S., Baichoo, S., Mungloo-Dilmohamud, Z. & Jaufeerally-Fakim, Y. (2018) Comparison of genomic islands in cyanobacteria: evidence of bacteriophage-mediated horizontal gene transfer from eukaryotes., Microbiological Research, 211:31-46.

Godde, J.S. (2016) "Histone acetylation/deacetylation" in Salem Encylopedia of Health and Medicine: Cancer, 2nd Ed., Vol. 3, 803, Grey House Publishing: Armenia, NY

Godde, J.S. (2015) "Studying Abroad" in Salem Health: Adolescent Health & Wellness, 941-943, Grey House Publishing: Armenia, NY

Godde, J.S. (2012) Breaking through a phylogenetic impasse: a pair of associated archaea may have played host in the endosymbiotic origin of eukaryotes., Cell & Bioscience, 2:29.

Godde, J.S. (2012)  “DNA Analysis” in Encyclopedia of Applied Sciences, 515-520, Salem Press: Pasadena, CA.

Godde, J. S. (2011) “Biopiracy and Bioprospecting” in Encyclopedia of Environmental Issues, Revised Ed., 162-164, Salem Press: Pasadena, CA.

Coyne, M. S. & Godde, J. S. (2010) “Environmental Biotechnology” in Encyclopedia of Global Resources, 372-375, Salem Press: Pasadena, CA.

Gossett, D. R. & Godde, J. S. (2010) “Biotechnology” in Encyclopedia of Global Resources, 124-129, Salem Press: Pasadena, CA.

Godde, J. S. (2010) “Wolf-Hirschhorn Syndrome” in Genetics and Inherited Disorders: Revised Edition, Vol. 3, 1242-1243, Salem Press: Pasadena, CA.

Godde, J. S. (2010) “Genetic Resources” in Encyclopedia of Global Resources, Vol. 2, 490-494, Salem Press: Pasadena, CA.

Godde, J. S. (2009) “Biotechnology” in Encyclopedia of Global Warming, Vol. 1, 142-145, Salem Press: Pasadena, CA.

Godde, J. S. & Ura, K. (2009) Dynamic alterations of linker histone variants during development., Int. J. Dev. Biol., 53:215-224.

Godde, J. S. (2008) “Chromosomes and cancer” in Salem Encyclopedia of Health and Medicine: Cancer, Vol. 1, 274-276, Salem Press: Pasadena, CA.

Godde, J. S. (2008) “STR (short tandem repeat) analysis” in Encyclopedia of Forensic Science, Vol. 3, 920, Salem Press: Pasadena, CA.

Godde, J. S. & Ura, K. (2008) Cracking the enigmatic linker histone code., J. Biochem. 143:287-293.

Godde, J. S. (2007) “Last human chromosome sequenced” in Magill’s Medical Encyclopedia, 4th rev. ed., Vol. 2, 1122, Salem Press: Pasadena, CA.

Godde, J. S. & Bickerton, A. J. (2006) The repetitive DNA elements called CRISPRs and their associated genes: evidence of horizontal transfer among prokaryotes., J. Molec. Evol., 62, 718-729.

Godde, J. S. (2005) “Genomics” in Magill’s Medical Encyclopedia, 3rd rev. ed., 1066-1070, Salem Press: Pasadena, CA.

Godde, J. S. (2004) “Telomere Length in Clones” in Encyclopedia of Genetics, rev. ed., 730, Salem Press: Pasadena, CA.

Feig, J., Hussein, Y., & Godde, J. S. (2001) Combinatorial libraries of porphyrin derivatives: finding G-quadruplex interactive agents with a high specificity for human telomeric repeats., J Biomol. Struct. Dyn., 18, 967.

Goldman, K., Lembeck, M., & Godde, J. S. (1999) Probing the structure of (CGG)n triplet repeats in the human FMR1 gene via interstrand crosslinking., J Biomol. Struct. Dyn., 16, 1274-1275.

Goldman, K., Donaire, M., & Godde, J. S. (1998) Mapping mitomycin crosslink sites in the human Fragile X gene., National Minority Research Symposium Proceedings., 88.

Godde, J. S., Kas, S.U., Hirst, M. & Wolffe, A.P. (1996) Nucleosome assembly on methylated CGG triplet repeats in the Fragile X Mental Retardation Gene 1 promoter., J. Biol. Chem., 271, 24325-24329.

Godde, J. S., & Wolffe, A.P. (1996) Nucleosome assembly on CTG triplet repeats., J. Biol. Chem., 271, 15222-15229.

Godde, J. S., Nakatani, Y., & Wolffe, A.P. (1995) The amino-terminal tails of the core histones and the translational position of the TATA box determine TBP/TFIIA association with nucleosomal DNA., Nucleic Acids Research., 23, 4557-4564.

Godde, J. S., & Wolffe, A.P. (1995) Disruption of reconstituted nucleosomes: the effect of particle concentration, MgCl2 and KCl concentration, the histone tails and temperature., J. Biol. Chem., 270, 27399-27402.

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